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Patient safety has & always will be Aguettant's priority. Our teams are focused on the development of a range of health products adapted to the challenges of daily medical practice.

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See the testimony of Professor William Harrop-Griffiths, Consultant Anaesthetist, Imperial College Healthcare NHS Trust, London, United Kingdom

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What do professional medical organisations say about pre-filled syringes ?
Association of Anaesthetists

Handling injectable medications in anaesthesia

‘Prefilled syringes have multiple advantages, and their purchase and use should be promoted.’ (2)

‘Purchase ready-to-administer products wherever possible. Prefilled syringes have the following advantages: reduction in labelling errors; reduction in bacterial contamination; potential for tamper-evidence; and potential for medication recognition mechanisms’. (2)

Royal Pharmaceutical Society

Professional guidance on the safe and secure handling of medicines

‘Medicines are presented as pre-filled syringes or other ‘ready-to-administer’ preparations wherever possible’. (3)

Association of Anaesthetists

Implementing human factors in anaesthesia: guidance for clinicals, departments and hospitals

‘Use pre-filled syringe if available. E.g. for emergency drugs such as Metaraminol, Ephedrine and Atropine.’ (1)

EAHP Special Interest Group Report

Prefilled syringes in intensive care units and operating theatres

‘Prefilled syringes can also support patient safety improvement as well as medication error and medicine waste reduction’ (4)


Our polypropylene syringes are pre-filled and ready-to-use in sterile packaging.

We strive to design innovative, ready-to-administer solutions to prevent medication errors, especially in emergency situations. (6)

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Ready to Administer

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Reduction of

medication errors


“A significant number of the potential human factor error steps in preparation of injectable medicines can be completely eliminated when using prefilled prelabelled syringes." (5)

It has been proven that "Medication errors were 17 times less likely when prefilled syringes were used". (6)


Reduction of

microbial contamination


"Prefilled syringes have zero contamination as against 6% for manually prepared syringes." (5) (7)


Reduced administration



When fast administration is essential, hand-preparing drugs at the bedside can result in delays in treatment. (6)

Ready-to-use pre-filled syringes eliminate preparation time, making them a suitable solution for emergency situations.


Reduced risks of injuries

for healthcare professionals


Use of pre-filled syringes eliminates needle-stick and cut injuries when opening glass ampoules. (8)


Waste and

waste reduction


Up to 86% of injectable drugs prepared in advance in the operating theater and intensive care are discarded at the end of the day. (9)

Considering all components used in the preparation steps of ampoules (syringe, drug, needle, pad, diluent…etc), pre-filled syringes could reduce your overall plastic use and the amount of waste you send to incinerators.


Time saving

for caregivers

The preparation time for the syringes is time-consuming for healthcare staff.

Opting for pre-filled syringes means spending more time with patients.
(1) Kelly et al. Anaesthesia. Implementing human factors in anaesthesia: guidance for clinicians, departments and hospitals. 2023. Available from:
https://associationofanaesthetists- publications.onlinelibrary.wiley.com/doi/10.1111/anae.15941
(2) Kinsella et al. Anaesthesia. Handling injectable medications in anaesthesia. 2023. Available from:
(3) Royal Pharmaceutical Society. Professional guidance on the safe and secure handling of medicines. 2024. Available from:
(4) EAHP. SIG special interest group report. Prefilled syringes in intensive care units and operating theatres. 2023. Available from:
(5) Preckel B et al. Ten years of the Helsinki Declaration on patient safety in anaesthesiology. Eur J Anaesthesiol 2020; 37:521–610
(6) Adapa RM, Mani V, Murray LJ, Degnan BA, Ercole A, Cadman B, Williams CE, Gupta AK, Wheeler DW. Errors during the preparation of drug infusions: a randomized controlled trial. Br J Anaesth. 2012 Nov;109(5):729-34. doi: 10.1093/bja/aes257. Epub 2012 Jul 31. PMID: 22850220.
(7) Gargiulo DA, Mitchell SJ, Sheridan J, et al. Microbiological contamination of drugs during their administration for anesthesia in the Operating Room. Anesthesiology 2016; 124; 785-794.
(9) Barbariol F, Deana C, Lucchese F, Cataldi G, Bassi F, Bove T, Vetrugno L, De Monte A. Evaluation of Drug Wastage in the Operating Rooms and Intensive Care Units of a Regional Health Service. Anesth Analg. 2021 May 1;132(5):1450-1456.
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6 March 2024